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Sunday, August 2, 2020

Marijuana Use Linked To Heart Disease Risk, Disruptions In Other Medications

BOSTON — Measures legalizing marijuana are becoming more common in the United States. As recreational and medicinal usage rises, cardiologists warn there are potential risks to this growing trend. According to a new study, as many as two million heart disease patients are current or former marijuana users.

Researchers behind the study also draw concerning parallels between tobacco and pot use.

Read more on StudyFinds
Medical marijuana often replaces other headache medications, small study shows

Most patients in a small cohort used medical marijuana in lieu of other abortive prescriptions to alleviate migraine pain, according to recent findings.

The researchers found that of the 25 patients who were still using medical marijuana at the time of the follow-up interview, 25% said they used it daily and 71.4% used it at least twice weekly.

 Before using medical marijuana, 46.4% of patients were using abortive medications 10 or more days monthly; only 25% did so after starting medical marijuana treatment, according to the researchers. Half of the patients used a THC-dominant strain of the substance and 71.4% used an inhaled form. The most common adverse events reported were dry mouth/throat (46.4%), dry/red eyes and fatigue/lethargy (35.7% each) and increased appetite (35.7%).

Read more on Healio 
Study finds that  CBD may help ease the disorder and Addiction to the high of weed

(CNN)Smoking weed has become a popular pastime, boosted by a more permissive social attitude and a relaxation of laws and regulations.

Marijuana use disorder encompasses both addiction and dependency, and is characterized by impairments in psychological, physical or social functioning. In the United States, research shows some 2.5% of adults, or about 6 million people, had suffered from marijuana use disorder in the past year, while 6.3% had the disorder at some point in their lives.

Read more on CNN
How much do we know about marijuana’s medical capabilities

Colorado, California and a few other states are leading the way, steering tax dollars from marijuana legalization toward controlled, peer-approved studies assessing the medical effectiveness of cannabis compounds.

Question for Medical Marijuana Users

When it comes to marijuana and two of its key components, THC and CBD, “there are a lot of claims, and like anything people are using or consuming there needs to be the research behind it to validate those claims,” said Chad Kinney, director of the state-funded Institute of Cannabis Research and professor of chemistry at Colorado State University Pueblo. 

Read more on Colarado Sun

CBD may help avert lung destruction in COVID-19

Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say.

"ARDS is a major killer in severe cases of some respiratory viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and we have an urgent need for better intervention and treatment strategies," says Dr. Babak Baban, immunologist and interim associate dean for research at DCG and corresponding author of the study in the journal Cannabis and Cannabinoid Research.

Read more on Medical Express 

Question for Medical Marijuana Users

A New Bill is Filed to Federally Legalize Marijuana

Yet another day and another senator files a new bill to legalize marijuana with a twist. The bill says that marijuana must be federally legalized and regulated like tobacco. This piece of legislation would remove cannabis from several different acts including the Controlled Substances Act (CSA).

The proposed bill ‘’Substance Regulation and Safety Act’’ would remove marijuana from the microscope and focus more on evaluating the risks and medical uses of marijuana. The U.S. Department of Health and Human Services (HHS) would be responsible for coming up with proper regulation to test and regulate marijuana just like tobacco. They will also impose quality control standards and also responsible for detecting THC-impaired driving.

The proposed bill states ‘’The descheduling provisions are retroactive and shall apply to any offense committed, case pending, or conviction entered, and, in the case of a juvenile, any offense committed, case pending, or adjudication of juvenile delinquency entered, before, on, or after the date of the enactment of this Act.

Question for Medical Marijuana Users

HHS would have to come up with a national strategy to prevent youth use and abuse of cannabis, with specific attention to youth vaping of cannabis products. Further, the text of the legislation states that the department would be required to “regulate cannabis products in the same manner, and to the same extent,” as it does with tobacco.’’ (Source - Marijuana Moment)

This also includes all the policies regarding the advertisement and marketing of tobacco will also be applied in the case of marijuana products as well.

The bill proposed by Senator Tina Smith was greatly appreciated by the marijuana community and her efforts to cannabis reforms will be remembered. However, with the recent rejection of the Marijuana Legalization Amendment 2020 by the democratic party, chances for federal legalization are quite slim.

Thursday, July 30, 2020

Study: Scientists modified a strain of cannabis to kill cancer cells

It is known far and wide that there are many chemical compounds inside the Cannabis plant that could prove to be beneficial for the human body. Especially CBD, which is the most common compound found in a Cannabis plant is effective in treating many types of diseases. There have been many presumptions about CBD and cancer but a recent study put things to bed and make everything crystal clear.

Cancer researcher Matt Dun, of the University of Newcastle in Australia, recently revealed that a modified strain of cannabis can destroy certain types of cancer cells while remaining harmless to the rest of the body. This research was going on for about 3 years and the researcher worked in collaboration with the Australian Natural Therapeutics Group (ANTG).

In a press release, Matt Dun said “ANTG wanted me to test it against cancer, so we initially used leukemia cells and were really surprised by how sensitive they were. At the same time, the cannabis didn’t kill normal bone marrow cells, nor normal healthy neutrophils [white blood cells]’’.

“We then realized there was a cancer-selective mechanism involved, and we’ve spent the past couple of years trying to find the answer.” He said. 

The researchers ran many trials including a number of cannabis strains. Some of them had the majority concentration of THC and an insignificant concentration of CBD while some strains had CBD and lacking the THC content. 

Furthermore, Dr. Matt Dun also said “There are trials around the world testing cannabis formulations containing THC as a cancer treatment, but if you’re on that therapy your quality of life is impacted. You can’t drive, for example, and clinicians are justifiably reluctant to prescribe a child something that could cause hallucinations or other side-effects’’.

“The CBD variety looks to have greater efficacy, low toxicity, and fewer side-effects, which potentially makes it an ideal complementary therapy to combine with other anti-cancer compounds.”

Question for Medical Marijuana Users

The next phase for the study includes investigating what makes cancer cells sensitive and normal cells not, whether it is clinically relevant, and whether a variety of cancers respond.

He also added, “We need to understand the mechanism so we can find ways to add other drugs that amplify the effect, and week by week we’re getting more clues. It’s really exciting and important if we want to move this into a therapeutic’’.

“Hopefully our work will help to lessen the stigma behind prescribing cannabis, particularly varieties that have minimal side-effects, especially if used in combination with current standard-of-care therapies and radiotherapy. Until then, though, people should continue to seek advice from their usual medical practitioner.” - Source - NewCastle 

Studies like this from Matt Dun are inspiring scientists from around the world to do more research into Cannabis and find more medical uses of Cannabis. Many experts have shared their concerns about not having large-scale experiments on Cannabis to find about more compounds inside the plant. But many recent studies revealed the Cannabis ''may'' treat cancer symptoms but now we know for sure that Cannabis can actually ease the symptoms as well as kill the cancerous cells in our body.

But, is this study enough to convince medical experts that Cannabis could actually treat and kill cancer cells? I don’t think so. At this point, even after the legalization of Cannabis, doctors and medical experts are still not prescribing medical cannabis to their patients and still considering it as a gateway drug. We’ll need more studies and testing to convince these people that Cannabis is the key element in treating cancer.

Also Read:

Democratic Party Rejected Marijuana Legalization Amendment 2020